Middle aged female bounded to wheel chair 🪑

CHIEF COMPLAINTS:-
A 39yr old lady, right handed individual, who is a house wife presented with a chief complaints of 
1.Inability to walk since 6mnths
2.burning sensation from chest to toes

HOPI:-
Pt was a/a 6 months back when she went out for a evng walk near her home had sustained a fall due to slippage on a slippery surface. Following the event she herself got up and reached home with a pain in left hip. Over the next two day's she developed a insidious onset tight band like sensation all around the chest at the level of xiphisternum f/b abnormal Tingling sensation, burning sensation below the xiphisternum to toes . In next couple of day's she noticed difficulty in sitting or getting up from a chair or lying down position or turning on bed. She also noticed stiffness in both lower limbs.
Though she was unable to walk she used to crawl with help of upper limbs & do her routine activities like mixing food, grooming, washing clothes...etc but after 1mnth she started noticing stiffness in her upper limbs & difficulty in doing above all activities.
No electric shock like sensation radiating to leg & no shock like sensation on bending neck.
No sharp shooting pain in particular dermatomal pattern
No c/o neck or upper limb muscle weakness / respiratory distress
No muscle fasciculations/ wasting
No h/o Headache/vomiting/seizure/ speech abnormality/alteration in behaviour/reccurent hiccups
No h/o urinary urgency/frequency/ retention.
No h/o palpitation/postural dizziness/ loss of sweating.
No h/o any impairment in  vision/ hearing/ speech/ chewing & swallowing.
No h/o skin rash,oral ulcers, alopecia, dryness of mouth.
No h/o wt loss, decreased appetite, 
No h/o or contact to TB
No h/o recent vaccination / bleeding diathesis.
No h/o trauma In back

PAST HISTORY:-
No significant past history
No h/o Animal bite/ vaccination
No h/o blood transfusion

FAMILY HISTORY:-
No h/o similar complaints in family members
PERSONAL HISTORY:-
Diet- vegetarian , Takes  egg🥚
Sleep- Adequate
B×B - Normal
No addictions /high risk behaviour

SUMMARY:-
A 39 yr old female with out any pre existing comorbidity developed chronic progressive spastic Quadriparesis ( LL > UL ) associated with decreased pain, Temp, vibration & joint position sensation in both LL , Trunk, upto Xiphisternum & feels a band like sensation at that level. Without bladder & bowel & clinically cranial nerve involvement.

GENERAL PHYSICAL EXAMINATION:-
Pt is conscious/ alert/ cooperative
Facies- Normal
Built- moderate
Nutrition- BMI- 22kg/m2
Decibitus- Legs extended at Hip, knee & plantar flexed
PICCLE - Absent
PR- 86bpm, regular, normal volume, no radio radial or radio femoral delay
BP- 130/80mmhg in supine
RR- 16cpm, Thoraco abdominal type
Temp- 98.6f
No engorged neck veins/ enlarged neck glands/ no oral ulcers / no neuro cutaneous markers
Cranium & spine normal, No vertebral tenderness noted.

HIGHER MENTAL FUNCTIONS:-
Pt is rt handed 
GCS- 15/15
Conscious/ well Oriented to time place & person.
Memory- Immediate, recent, remote intact.
Speech- Normal

CRANIAL NERVES:-
Normal

MOTOR:-
Muscle bulk preseved in all limbs.
No fasciculations/ wasting seen.
Attitude-
Pt lying supine position with attitude of both lower limbs extended at Hip , knee & flexed at ankle
Both arms placed at sides 
Nutrition-
                           Rt.                     Lt.
Arm.                  24cm.              24cm
Fore arm.         19cm.              19cm
Thigh.               43cm.              42cm
Calf.                  32cm.              32cm

TONE-
According to modified ashworth scale
Grade 1 spasticity in U/L
Grade 2 Spasticity in L/L

POWER-
UPPER LIMB-.                    
                             Rt.                   Lt
Shoulder
 Abduction.         4/5.                4/5
 Adduction.         4/5.                4/5
 Flexion.              4/5.                 4/5
 Extension.          4/5.                4/5

Elbow
 Flexion.               4/5.                4/5
 Extension.           4/5.               4/5

Wrist
 Dorsiflexion.       4/5.               4/5
 Palmar flexion.   4/5.               4/5

Small muscles of both hands - 4/5

LOWER LIMB-                  
                             Rt.                  Lt
HIP
 Abduction.          4/5.              4/5
 Adduction.          4/5.              4/5
 Flexion.               4-/5.              4-/5
 Extension.          4/5.               4/5

KNEE
 Flexion.              4/5.               4/5
 Extension.         4/5.                4/5

ANKLE
 Dorsiflexion.      4/5.               4/5
 Plantar flexion. 4/5.                4/5

Small muscles of foot- 4/5

REFLEXES:-
                  Rt.            Lt
B.              3+.            3+
T.              3+.            3+
S.              3+.           3+
K.              3+.            3+
A.              2+.           2+
PLANTAR B/L extensor
Abdominal reflex:- absent

SENSORY:-
spino thalamic
Crude touch,Pain,Temperature
She feels burning sensation below xiphisternum to feet & can't perceive any other 

Post.column:-
Fine touch, Vibration,Proprioception- Decreased from xiphisternum, hip, knee, Ankle, in graded manner . 75%, 50%, 25% 0%

CEREBELLUM:-
no nystagmus, giddiness, FNF- normal
HKT- couldn't be tested

GAIT- couldn't be tested since even with 2 people support she couldn't walk & has her both legs stiff

MENINGEAL SIGNS:-
Absent

ANS:-
Resting tachycardia, abnormal sweating absent

OTHER SYSTEMS:-
CVS:- Apex beat in left 6th ICA 1cm medical to mid clavicular line
S1S2 heard no murmers
No raised jvp, engorged veins
RS:-
Bae+, Nvbs, No added sounds
ABDOMEN:-
Soft, non tender, no organomegaly

DIFFERENTIAL DIAGNOSIS:-
With the above history I would like to localize the lesion to Dorsal spinal cord at the level of T4 since it started acutely & involving most of the tracts probably Non compressive myelopathy.

Demyelinating ( MS / NMOSD )
Vitamin Deficiency - B12
Vascular
Infective
Para neoplastic


CSF- 4 cells, lymphocytes
Serology- negative
Hb- 14.5gm/dl
TLC- 6,500
Plt- 2.6lakh
MCV- 92

B12 injection daily for 5days given, pt report's improvement in sensory symptoms & pt noticed that she can flex her lower limbs now






Gait video link at admission:-

 https://drive.google.com/file/d/1aQ_8_gNvVz6yPGpYMAA2RlCTgtGjh-AI/view?usp=drivesdk




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